Blood Biomarkers and Atrial Remodeling in 511 Subjects at Risk of Atrial Fibrillation

511 subjects, including 286 endurance athletes and 225 patients with arterial hypertension, underwent echocardiography and blood sampling for biomarker analysis. Filip Loncaric published this dataset on figshare in May 2026. The study assessed biomarkers of myocardial damage, vascular endothelial dysfunction, and fibrosis in relation to atrial remodeling.

Use Cases

• Analyze relationships between patient characteristics and biomarker levels based on age, gender, BMI, and renal function.
• Compare biomarker profiles between endurance athletes and hypertensive patients.
• Investigate associations between fibrosis biomarkers like Galectin-3 and left atrial reservoir strain.
• Build predictive models for atrial remodeling using echocardiographic parameters and serum biomarkers.
• Validate potential biomarkers for atrial fibrillation risk in specific populations.

Strengths

• 511 subjects provide a substantial cohort for analysis.
• Includes 2D and 3D echocardiography with speckle-tracking analysis.
• Analyzes a panel of 10+ specific biomarkers across three functional categories.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Data may reflect bias inherent to the specific cohort of athletes and hypertensive patients.

Provenance

Source

figshare

Collection Method

Clinical study involving echocardiography and blood sampling.

Freshness

Last updated 2026-05-21 22:01:28; freshness should be verified.