AIP and Prediabetes Risk Associations in 100,473 Chinese Adults

100,473 Chinese adults with baseline fasting plasma glucose under 5.6 mmol/L were analyzed for incident prediabetes risk. The study, authored by Bing Wang and shared on figshare, investigates nonlinear associations between the atherogenic index of plasma (AIP) and prediabetes, stratified by BMI categories. Results from a median 3.0-year follow-up show 12,371 incident cases and identify BMI-specific risk thresholds.

Use Cases

• Modeling nonlinear risk associations between lipid markers and dysglycemia based on AIP values.
• Investigating effect modification by body mass index categories based on BMI-stratified analyses.
• Identifying inflection points for clinical risk thresholds based on model-derived AIP values.
• Replicating Cox regression and restricted cubic spline analyses for prediabetes outcomes.

Strengths

• Large cohort of 100,473 participants provides statistical power.
• Median follow-up period of 3.0 years for longitudinal analysis.
• Clear outcome definition of FPG-defined incident prediabetes (5.6-6.9 mmol/L).

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Data may reflect geographic bias inherent to the Chinese adult cohort studied.

Provenance

Source

Bing Wang

Collection Method

Analysis of baseline health examination data using restricted cubic spline and Cox regression.

Time Range

Median follow-up of 3.0 years.

Freshness

Last updated 2026-05-14 14:26:00; freshness should be verified.

Geography

Chinese adult population.