Data Sheet 1_Borderline liver enzyme patterns and their metabolic–inflammatory signatures:

A clinical dataset of 800 adult outpatients with standardized fasting biochemistry and hematology panels analyzed at baseline and a three-month follow-up. The study, conducted at Elazığ Fethi Sekin City Hospital between October 2024 and January 2026, investigates distinct metabolic and inflammatory signatures associated with hepatocellular and cholestatic liver enzyme patterns in patients with borderline elevations. The data includes clinical, biochemical, inflammatory, and iron parameters, with results analyzed using multivariable logistic regression.

Use Cases

• Identify distinct metabolic subphenotypes based on hepatocellular versus cholestatic liver enzyme patterns.
• Model associations between borderline enzyme elevations and biomarkers like ferritin, HbA1c, and the Systemic Immune-Inflammation Index (SII).
• Validate sex-specific reference ranges for liver enzymes in outpatient risk stratification.
• Investigate the relationship between iron transport markers and hepatocellular liver enzyme patterns.

Strengths

• Includes 800 patient records with standardized biochemistry and hematology panels.
• Provides longitudinal data with baseline and three-month follow-up measurements.
• Analysis includes multivariable logistic regression results with odds ratios and confidence intervals for key associations.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count for specific subcategories is unknown, which may limit suitability assessment.
• Data is from a single-centre study, which may reflect geographic bias inherent to the source.

Provenance

Source

figshare

Collection Method

Single-centre observational outpatient study with standardized fasting biochemistry and hematology panels.

Time Range

October 2024 to January 2026

Freshness

Last updated 2026-05-15 04:24:01; freshness should be verified.

Geography

Elazığ Fethi Sekin City Hospital