Data Sheet 1: TCD Bubble Test for PFO Detection in Young Stroke Patients

Anna Bogdanova's data sheet contains results from a retrospective analysis of a prospective institutional stroke registry. It includes data from 383 acute ischemic stroke patients aged ≤65 years treated over 5 years, with 120 undergoing transcranial Doppler bubble testing. The study evaluated the diagnostic accuracy of the bubble test for detecting a patent foramen ovale.

Use Cases

• Calculate diagnostic test performance metrics (sensitivity, specificity, PPV, NPV) based on the reported bubble test and TEE results.
• Analyze the association between right-to-left shunt status and patient outcomes based on the described cardiovascular risk profiles and functional outcomes.
• Determine an optimal diagnostic threshold for bubble tests based on the reported ROC analysis and cut-off of ≥3 bubbles.

Strengths

• Includes data from 383 patient records over a 5-year period.
• Reports specific diagnostic performance metrics, including a sensitivity of 97.1% and specificity of 71.2%.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count for the underlying data is unknown, which may limit suitability assessment.
• The 722.0 KB file size suggests a limited scope of data.

Provenance

Source

Prospective institutional stroke registry, retrospectively analyzed.

Collection Method

Clinical registry data collection and diagnostic testing.

Time Range

Data collected over 5 years (specific years not provided).

Freshness

Last updated 2026-05-11 04:21:13; freshness should be verified.