Data Sheet 1: Calcium and SctV-SctW Interaction in Type III Secretion

A research article investigating the molecular mechanism of calcium regulation in bacterial Type III secretion systems. The study demonstrates high-affinity calcium binding by the gatekeeper protein SctW and export apparatus component SctV, showing how calcium modulates their interaction to control the secretion switch from translocators to effectors. The work was authored by Athina G. Portaliou and published on figshare under a CC-BY-4.0 license in May 2026.

Use Cases

• Modeling protein-protein interaction dynamics based on calcium concentration described in the study.
• Training classifiers to predict secretion states based on the described SctV-SctW affinity states.
• Analyzing sequence-structure relationships for calcium-binding sites in secretion system components.

Strengths

• The dataset is a 1.1 MB PDF providing detailed experimental findings on a specific molecular mechanism.
• The research is clearly attributed to a specific author and published under a permissive CC-BY-4.0 license.
• The description provides a specific and detailed biological hypothesis and experimental conclusion.

Limitations

• The primary content is a research article, not a structured dataset of observations or measurements.
• Row count and column-level documentation are absent; the data is embedded within narrative text and figures.
• The 1.1 MB size suggests a small document, limiting the scale of directly extractable, machine-readable data.

Provenance

Source

Athina G. Portaliou via figshare.

Collection Method

Likely contains experimental data from the described study on protein interactions and calcium binding.

Freshness

Last updated 2026-05-20 13:01:57.