Case Report: Erdheim–Chester Disease with Liver Involvement Treated with Trametinib

A 2026 case report from figshare details a patient with Erdheim–Chester disease (ECD) and liver involvement. The report, authored by Long Chang, describes a successful therapeutic response to trametinib, as evidenced by follow-up liver function tests and FAPI-PET/CT imaging performed six months after treatment initiation. The dataset consists of a single 3.2 MB DOCX file.

Use Cases

• Analyzing clinical presentation patterns of Erdheim–Chester disease based on the described case of liver enzyme elevation.
• Studying treatment efficacy for non-BRAF-V600E mutant ECD based on the reported response to trametinib.
• Reviewing diagnostic imaging findings based on the mention of FAPI-PET/CT results.
• Compiling rare disease case literature for meta-analysis based on the detailed clinical narrative.

Strengths

• Case report includes specific follow-up data from liver function tests and FAPI-PET/CT imaging.
• Dataset is openly available under a CC-BY-4.0 license.
• File is a single, downloadable 3.2 MB DOCX document.

Limitations

• Row count and column-level documentation are unknown, limiting suitability assessment.
• The dataset is a single case report, which may not be generalizable.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

figshare, author Long Chang.

Collection Method

Likely a documented clinical case study.

Freshness

Last updated 2026-05-29 04:44:22; freshness should be verified.