Cerebral Air Embolism Case Review in Interventional Pulmonology

A systematic review of 53 documented cases of cerebral air embolism (CAE) related to interventional pulmonology procedures. The analysis covers epidemiology, pathophysiology, clinical manifestations, and treatment from January 2001 to December 2024. It proposes a procedure-specific preventive framework for improving patient safety.

Use Cases

• Analyze the epidemiology of CAE, including its reported incidence of 0.02 to 0.4% and mortality rates up to 20-30%, across the 53 reviewed cases.
• Study the relationship between specific interventional pulmonology procedural steps and the pathophysiological mechanisms of CAE described in the review.
• Examine the clinical manifestations and treatment outcomes documented in the 53 case reports to inform diagnostic and intervention guidelines.

Strengths

• Systematic review methodology, searching multiple databases including PubMed, Scopus, Web of Science, Wanfang, CNKI, and VIP.
• Focuses on a specific, rare complication with a defined scope of 53 human case reports.
• Includes a proposed evidence-based, procedure-specific preventive framework for clinical application.

Limitations

• Small sample size of only 53 cases, limiting statistical power and generalizability of findings.
• Relies on published case reports, which may introduce publication bias and inconsistent data reporting.
• The data is presented in a narrative review format within a DOCX file, not in a structured, machine-readable tabular format.

Provenance

Source

Systematic search of PubMed, Scopus, Web of Science, Wanfang, CNKI, VIP, and other databases, supplemented by manual retrieval.

Collection Method

Systematic review of human case reports related to cerebral air embolism induced by interventional pulmonology.

Time Range

January 2001 to December 2024

Freshness

Last updated March 2026, covering literature through December 2024.

Geography

Global (cases sourced from international literature databases)