Helicobacter pylori Outer Membrane Vesicle Characterization Over Time and Phenotypes

A 239.9 KB dataset from figshare, authored by Valentina Puca and last updated in April 2026. It characterizes Helicobacter pylori Outer Membrane Vesicles (OMVs) from planktonic and biofilm phenotypes over 2, 6, and 10 days. The data includes measurements of vesicle number, size, and proteomic composition, linking bOMVs to virulence and potential tumorigenesis.

Use Cases

• Modeling OMV size and quantity dynamics based on bacterial growth time and phenotype mentioned in the description.
• Analyzing proteomic enrichment of virulence factors in early growth phases versus metabolic factors in later phases.
• Investigating the role of biofilm-derived OMVs in iron accumulation, oxidative stress protection, and immunosuppression.
• Correlating vesicle characteristics with bacterial biofilm structure and viability over time.

Strengths

• Data is derived from multiple analytical techniques: transmission electron microscopy, nanoparticle tracking analysis, dynamic light scattering, electrophoretic light scattering, and proteomics.
• Experimental design includes three time points (2, 6, and 10 days) and two bacterial phenotypes (planktonic and biofilm).
• Released under a permissive CC-BY-4.0 license for reuse.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is small (239.9 KB), indicating limited scope, likely containing summary results rather than raw experimental data.

Provenance

Source

figshare

Collection Method

Data generated from laboratory analysis of Helicobacter pylori ATCC 43629 cultures.

Time Range

Experimental observations over 2, 6, and 10 days.

Freshness

Last updated 2026-04-20 05:22:30; freshness should be verified.

Geography

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