Data Sheet 1_Clindamycin susceptibility and virulence characterization of Listeria monocyt

Aida Pérez-Baltar contributed genomic and phenotypic data for 62 Listeria monocytogenes strains isolated from meat and meat-processing environments. The dataset, last updated in May 2026, includes clindamycin susceptibility profiles, minimum inhibitory concentration values, and the presence of resistance and virulence genes. Whole-genome sequencing was used to explore relationships between antimicrobial resistance and virulence factor truncations.

Use Cases

• Correlating clindamycin susceptibility phenotypes with specific genetic mutations based on MIC and disk diffusion results
• Identifying hypovirulent strains based on truncated or impaired virulence genes like prfA, inlA, and actA
• Comparing genomic profiles of strains belonging to different clonal complexes (CC31, CC155) for surveillance studies
• Investigating the co-occurrence of intrinsic antibiotic resistance genes (fosX, norB, mprF, sul) with acquired resistance markers

Strengths

• Includes 62 distinct bacterial strains with both phenotypic and genotypic characterization
• Reports specific MIC values (0.25–0.5 μg/mL) for susceptible strains and identifies the vgaG resistance gene
• Links genomic findings (e.g., premature stop codons in inlA) to observed phenotypic outcomes like phospholipase C activity

Limitations

• Row count for the underlying data tables is unknown, which may limit suitability assessment
• Column-level documentation is absent; field semantics must be inferred after download
• The dataset is small in scale (583.1 KB), representing a limited sample size

Provenance

Source

figshare

Collection Method

Strains were isolated from meat and meat-processing environments, with susceptibility tested via disk diffusion and MIC determination, and genomes analyzed via whole-genome sequencing.

Freshness

Last updated 2026-05-21 05:44:22; freshness should be verified