Clinical Characteristics of Lean Diabetes in Aortic Stenosis Patients, 2011-2015

315 patients with moderate and severe aortic stenosis were stratified by body mass index and diabetes status in a retrospective cohort study from a tertiary medical center. Aloysius Sheng-Ting Leow published this analysis under a CC-BY-4.0 license, with data collected between September 2011 and December 2015. The study found that 14.9% of patients had lean diabetes, a phenotype associated with an 81% increased hazard of major adverse cardiovascular events.

Use Cases

• Risk stratification modeling based on the lean diabetes phenotype and cardiovascular comorbidities mentioned in the description
• Comparative survival analysis of patient subgroups defined by BMI and diabetes status over a 3.0 ± 2.1 year follow-up
• Investigating associations between clinical characteristics like age, hypertension, and coronary artery disease with major adverse cardiovascular events

Strengths

• Includes 315 patient records with a mean follow-up period of 3.0 ± 2.1 years
• Provides specific statistical results, such as an adjusted hazard ratio of 1.81 for major adverse cardiovascular events in the lean DM group
• Clear temporal scope from September 2011 to December 2015

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• Data may reflect geographic or institutional bias inherent to a single tertiary medical center

Provenance

Source

Echocardiographic database at a tertiary medical center

Collection Method

Retrospective cohort study

Time Range

September 2011 to December 2015, with follow-up of 3.0 ± 2.1 years

Freshness

Last updated 2026-04-23 05:34:52; freshness should be verified