Clinical and Immunological Profiles Across Frailty Subgroups in Hemodialysis Patients

A single-center observational study includes 66 maintenance hemodialysis patients categorized into Normal, Pre-Frailty, and Frailty groups. The dataset contains demographic, clinical, laboratory, physical performance, and immune cell subset data collected via flow cytometry. It was authored by Hongmei Liu and last updated on May 25, 2026.

Use Cases

• Correlating immune age with biological age based on immune cell subset data
• Comparing physical performance metrics like grip strength across frailty subgroups
• Analyzing associations between inflammatory cytokine levels and clinical frailty status
• Developing risk stratification models using combined clinical, functional, and immunological features

Strengths

• Includes 66 patient records with detailed frailty assessments using the Fried FRAIL scale
• Contains multi-modal data: clinical (HbA1c, ferritin), functional (grip strength, fall prevalence), and immunological (effector memory CD4+ T cells, Th1/Th2 ratios)
• Provides specific statistical results, such as grip strength values (18.00 kg in Frail vs. 26.70 kg in Normal) and correlation coefficients (r=0.98 in Normal group)

Limitations

• Row count is unknown, which may limit suitability assessment
• Column-level documentation is absent; field semantics must be inferred after download
• Data is from a single-center study, which may limit generalizability

Provenance

Source

figshare

Collection Method

Single-center observational study collecting demographic, clinical, laboratory, and flow cytometry data.

Freshness

Last updated 2026-05-25 06:03:03; freshness should be verified