Mycobacterial Co-infection Genomic and Clinical Case Data

Clinical and genomic data from a single-case study of pulmonary co-infection by Mycobacterium septicum and Mycolicibacterium nivoides. The dataset includes results from microbiological assays, genome sequencing of 20 colonies per species, virulence tests, and a literature review of 19 additional cases. Researcher Chengcheng Wang published the data on figshare in April 2026.

Use Cases

• Analyze intra-strain genomic heterogeneity by comparing sequences from 20 colonies per mycobacterial species.
• Correlate specific gene mutations (e.g., α/β hydrolase, papA2) with enhanced virulence measured in the Galleria mellonella model.
• Review clinical significance by examining curated data from 19 literature-reported cases of M. septicum infection.
• Investigate genome-based species classification using data from 16 re-analyzed publicly accessible genomes.

Strengths

• Includes genome sequencing data for 20 bacterial colonies from each of the two mycobacterial species.
• Integrates multiple data types: clinical case details, genomic sequences, virulence assay results, and a literature review.
• Dataset is recent, published in April 2026.

Limitations

• Very small scale (19.0 KB), derived primarily from a single clinical case study.
• Limited generalizability due to the focus on one patient co-infection.
• Row and column counts are unknown, limiting assessment of data structure.

Provenance

Source

figshare, authored by Chengcheng Wang.

Collection Method

Single-case study involving clinical data collection, microbiological assays, genome sequencing, virulence testing, and literature review.

Time Range

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Freshness

Published April 2026.

Geography

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