Colonoscopy-Detected High-Risk Adenomas and Alcohol Consumption in First-Degree Relatives

An observational case–control study of 210 first-degree relatives undergoing colonoscopy, published by Yuan Lin in 2026. The data includes baseline characteristics, lifestyle factors, fecal immunochemical test results, and serum biomarkers, used to build a prediction model for high-risk adenomas.

Use Cases

• Predicting high-risk adenoma presence based on lifestyle and clinical variables mentioned in the description.
• Evaluating the association between alcohol consumption and colorectal lesion risk among first-degree relatives.
• Assessing the clinical utility of a multivariable prediction model for risk stratification in screening programs.
• Analyzing the performance of fecal immunochemical tests and serum biomarkers as predictors of advanced lesions.

Strengths

• Includes data from 210 first-degree relatives, with 105 cases and 105 controls.
• Model performance was assessed using ROC curves, calibration analysis, and decision curve analysis.
• Data on multiple variable types, including lifestyle factors, clinical data, and laboratory results, were collected.

Limitations

• Row count for the underlying dataset is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The study notes no external validation was performed for the prediction model.

Provenance

Source

figshare

Collection Method

Data were collected from first-degree relatives undergoing colonoscopy as part of an observational case–control study.

Freshness

Last updated 2026-05-21 09:43:33; freshness should be verified.