LZH and ZJ Combined Treatment Study: Molecular Mechanisms in Skin Wound Healing

A research document describing a study on the combined effects of Lingzhi Huang capsules and Zeng Jian Health Tonic on skin wound healing. The 31.6 KB DOCX file details in vitro and in vivo experiments, including LC-MS/MS analysis, histopathology, and protein array profiling. The work was authored by Li Liu and last updated on June 2, 2026.

Use Cases

• Study the molecular mechanisms of traditional Chinese medicine formulations based on the described LC-MS/MS and protein array analyses.
• Investigate the role of BMP5 in ferroptosis and wound healing based on the mechanistic validation experiments described.
• Analyze the combined therapeutic effects on angiogenesis and oxidative stress based on the in vitro HUVEC cell assays mentioned.
• Explore network pharmacology approaches for identifying key signaling pathways in complex herbal treatments as described in the methods.

Strengths

• The study includes multi-modal validation through in vivo mouse models and in vitro cell culture experiments.
• Mechanistic insights are provided through specific protein targets like BMP5, GPX4, SLC7A11, and FTH1.
• The document is shared under a permissive CC-BY-4.0 license.

Limitations

• The dataset is a 31.6 KB DOCX file, indicating a limited scope focused on a single study's findings.
• Column-level documentation for any underlying raw data is absent; field semantics must be inferred after download.
• Row count for any potential tabular data within the document is unknown, which may limit suitability assessment.

Provenance

Source

figshare, authored by Li Liu.

Collection Method

Data was generated through laboratory experiments including LC-MS/MS, histopathological analysis, immunofluorescence, Western blotting, protein antibody arrays, and in vitro cell assays with HUVECs.

Freshness

Last updated 2026-06-02 05:42:34; freshness should be verified.