Comparative Efficacy of Pediatric Atopic Dermatitis Treatments: A Network Meta-Analysis

A March 10, 2025, systematic review by Liu Yang included 32 randomized controlled trials with 3,961 participants. The dataset contains the analysis results comparing treatments for pediatric atopic dermatitis, focusing on SCORAD and EASI score improvements. It is published under a CC-BY-4.0 license and was last updated on May 1, 2026.

Use Cases

• Ranking treatment efficacy for pediatric atopic dermatitis based on SCORAD and EASI score improvements.
• Comparing the performance of biologic drugs like Dupilumab against other interventions like Probiotics or Vitamin D.
• Informing clinical decision-making by identifying top-performing treatments from cumulative probability rankings.

Strengths

• Analysis is based on 32 randomized controlled trials, a substantial number for a meta-analysis.
• The study protocol is registered with PROSPERO (CRD420250650919), indicating a structured, transparent methodology.
• Results include specific efficacy rankings for treatments like Dupilumab (96.0%) and Pimecrolimus (99.9%).

Limitations

• The dataset is a 863.2 KB DOCX document; the underlying raw data tables are not provided separately.
• Column-level documentation is absent; field semantics must be inferred from the text after download.
• Row count is unknown, which may limit suitability assessment for direct computational analysis.

Provenance

Source

figshare

Collection Method

Systematic literature review and Bayesian network meta-analysis of published randomized controlled trials.

Time Range

Literature search deadline was March 10, 2025.

Freshness

Last updated 2026-05-01 05:24:53; freshness should be verified.