Comparative Study on Left Atrial Appendage Occluders in 231 AF Patients

A retrospective analysis of 231 atrial fibrillation patients undergoing a one-stop procedure combining catheter ablation and left atrial appendage occlusion. The dataset compares the 6-month peri-device leak rates and safety outcomes for three occluder devices: WATCHMAN, LAmbre, and LACBES. The data was uploaded by Haoqing Ren in 2026 under a CC-BY-4.0 license.

Use Cases

• Compare the sealing efficacy of different LAA occluder devices based on the reported 6-month peri-device leak rates.
• Analyze the relationship between CHA2DS2-VASc score and peri-device leak risk as identified in the multivariate analysis.
• Investigate the association between patient age and peri-device leak outcomes, given its identification as a protective factor.
• Assess the statistical power for rare safety endpoints like device-related thrombus and stroke across different device groups.

Strengths

• Includes data from 231 patients, providing a basis for comparative analysis.
• Reports specific peri-device leak rates for three device groups: 8.2% (WATCHMAN), 6.9% (LAmbre), and 4.1% (LACBES).
• Employs advanced statistical methods (Firth-corrected logistic regression, Cox models) to handle low event counts.

Limitations

• Row count and column-level documentation are absent; field semantics must be inferred after download.
• The statistical power for rare safety endpoints like DRT or stroke was reported as low, limiting definitive safety conclusions.
• The dataset is very small at 26.1 KB, indicating limited scope and likely summary-level data.

Provenance

Source

Haoqing Ren via figshare

Collection Method

Retrospective analysis of patient records.

Freshness

Last updated 2026-05-26 04:37:13; freshness should be verified.