Mouse Wound Healing Data for Polymyxin B Administration Routes

120 Kunming mice were used in a study comparing topical, intravenous, and combined Polymyxin B administration for wound infections. The dataset includes daily body weight changes, wound erythema observations, bacterial load counts, cytokine levels, and histopathological assessments collected over 17 days. Author Chenhu Ma published the data under a CC-BY-4.0 license on figshare in May 2026.

Use Cases

• Compare wound closure rates based on different drug administration routes described in the study
• Analyze bacterial clearance efficiency against multidrug-resistant Pseudomonas aeruginosa infection
• Model the relationship between cytokine levels (e.g., IL-1β, TNF-α) and wound healing progression
• Evaluate histopathological damage scores across treatment groups

Strengths

• Experimental design includes 120 mice across five distinct treatment groups for comparative analysis
• Data collection spans multiple modalities: bacterial load, cytokine detection, and histopathological assessment

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment

Provenance

Source

figshare

Collection Method

Laboratory experiment on a mouse wound infection model, with data collected from observations and tissue analysis.

Time Range

Experimental observations recorded over 17 days post-infection.

Freshness

Last updated 2026-05-18 05:43:13; freshness should be verified