Procalcitonin-Guided Antibiotic Therapy Compliance in Chinese Emergency ICU Patients, 2023

A retrospective study analyzed 195 adult patients with confirmed infections admitted to emergency intensive care units in China in 2023. Compliance with procalcitonin-guided antibiotic discontinuation guidelines was assessed, focusing on outcomes when PCT dropped below 0.5 ng/mL or decreased by ≥80%. The data likely contains patient-level metrics on compliance, mortality, ICU stay duration, antibiotic use, and antibiotic density.

Use Cases

• Analyzing the relationship between guideline compliance and patient mortality rates based on the reported 13.7% vs. 28.0% mortality difference.
• Evaluating the impact of early antibiotic discontinuation on ICU stay duration based on the reported 7 vs. 18 day difference.
• Studying the effect of timely discontinuation on antibiotic exposure based on the reported antibiotic density (5.0 vs. 22.0 DDDs).
• Investigating real-world adherence rates to PCT-guided algorithms in clinical practice based on the reported low timely discontinuation rate.

Strengths

• Based on a multicenter study of 195 patients, providing a sample size.
• Includes specific outcome metrics such as mortality rates (13.7%, 28.0%), ICU stay durations (7, 18 days), and antibiotic density (5.0, 22.0 DDDs).
• Focuses on a defined clinical guideline (PCT-guided antibiotic discontinuation) and a specific timeframe (2023).

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is described in a PDF report (323 KB), which may not be directly analyzable as structured data.

Provenance

Source

figshare, authored by Xiaojing Li.

Collection Method

Retrospective analysis of patient records from emergency intensive care units.

Time Range

2023

Freshness

Last updated 2026-05-18 04:10:39; freshness should be verified.

Geography

China