FADS3 Expression and Clinical Outcomes in Clear Cell Renal Cell Carcinoma

Data Sheet 1 contains bioinformatic and experimental analysis results for fatty acid desaturase 3 (FADS3) in clear cell renal cell carcinoma (ccRCC). The dataset was compiled by Si-Tao Chen from TCGA, GEO, and GTEx databases and includes results from Mendelian randomization, single-cell RNA sequencing, and functional assays. It was last updated on 2026-05-14.

Use Cases

• Investigate the association between FADS3 expression and patient prognosis based on clinical outcome data.
• Analyze the role of FADS3 in remodeling the tumor immune microenvironment based on single-cell RNA sequencing results.
• Study the link between lipid metabolism and oncogenic signaling pathways like PI3K/Akt in ccRCC.
• Validate FADS3 as a potential therapeutic target using in vitro functional assay results.

Strengths

• Integrates data from multiple authoritative genomic databases (TCGA, GEO, GTEx).
• Includes validation from multiple experimental methods (qRT-PCR, western blotting, functional assays).
• File size is 14.7 MB, indicating a substantial amount of structured data.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data may reflect the specific biases inherent to the source databases and the ccRCC focus.

Provenance

Source

TCGA, GEO, and GTEx databases.

Collection Method

Bioinformatic analysis, Mendelian randomization, single-cell RNA sequencing, and in vitro functional assays.

Freshness

Last updated 2026-05-14 04:29:27; freshness should be verified.