Cytokine Profiles in Maternal and Cord Blood from Term and Preterm Births

78 pregnancies provide paired maternal peripheral and umbilical cord blood samples analyzed for 48 cytokines, chemokines, and growth factors. The dataset, created by Tiantian Yu and shared via figshare, profiles immune signatures across term births, spontaneous preterm birth, and preterm birth with premature rupture of membranes. It was last updated in April 2026.

Use Cases

• Classify preterm birth subtypes (S-PTB, PROM-PTB) using cytokine levels like M-CSF, SCF, IFN-γ, and IL-2Rα from cord blood samples.
• Compare immune landscapes between maternal peripheral blood and cord blood compartments using profiles of 48 mediators.
• Identify coordinated cytokine correlation networks within the fetal immune milieu using the dataset's paired sample structure.
• Analyze immune remodeling by examining specific growth factor and chemokine changes, such as reductions in eotaxin and HGF in PROM-PTB.

Strengths

• Paired samples from 78 pregnancies enable direct maternal-fetal compartment comparisons.
• Profiles 48 specific immune mediators, including cytokines, chemokines, and growth factors.
• Includes three distinct clinical groups: term birth, spontaneous preterm birth, and preterm birth with premature rupture of membranes.

Limitations

• Small sample size of 78 pregnancies limits statistical power for subgroup analyses.
• Dataset is tiny at 784.0 KB, indicating limited scope and likely summary-level data.
• Unknown row count and specific column structure restrict detailed data exploration.

Provenance

Source

Tiantian Yu via figshare.

Collection Method

Multiplex profiling of cytokines, chemokines, and growth factors from collected blood samples.

Freshness

Last updated in April 2026.