Gut Microbiome Enterosignatures from Heat-Stressed Lactating Sows

Shotgun metagenomic data from 25 lactating sows exposed to heat stress conditions, decomposed into 8 taxonomic and 5 functional enterosignature subcommunities. The dataset, authored by Chiara Gini and last updated in April 2026, applies non-negative matrix factorization to reveal latent microbial assemblages linked to temporal and genetic-line effects. It is the first application of the enterosignature framework to study heat stress in livestock.

Use Cases

• Analyzing temporal shifts in microbial subcommunities based on taxonomic enterosignatures (T-ES) over a 14-day period.
• Investigating potential genetic-line effects on microbiome structure based on comparisons between TOL and SEN sows.
• Exploring functional restructuring of the microbiome based on KEGG Orthology (KO) profiles mapped to metagenome-assembled genomes (MAGs).
• Developing hypotheses for microbial ecology adaptation under heat stress using the enterosignature exploratory framework.

Strengths

• Data from 25 lactating sows provides a controlled biological cohort.
• Analysis yields 8 taxonomic and 5 functional enterosignature subcommunities for multi-faceted investigation.
• Includes statistical metrics (p-values, Cohen's d) for specific enterosignature shifts, such as T-ES 1 (p = 5.42e-4, d = 0.723).

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The description notes wide confidence intervals and non-significant omnibus tests for some effects, indicating uncertainty at the current sample size.

Provenance

Source

figshare

Collection Method

Shotgun metagenomes from sows exposed to heat stress, analyzed via non-negative matrix factorization (NMF).

Time Range

Covers a period from day 4 to day 14 of lactation under heat stress.

Freshness

Last updated 2026-04-10 18:01:14; freshness should be verified.

Geography

null