Research Data on Delphinidin-3-O-Glucoside Effects in a Neonatal Mouse HIE Model

A research article published on figshare by Jiacan Xu in May 2026. The study investigates the neuroprotective effects of Delphinidin-3-O-glucoside (Dp3G) on hypoxic-ischemic encephalopathy using in vitro microglial and in vivo neonatal mouse models. The 209 KB PDF includes results from transcriptomic analysis and molecular docking.

Use Cases

• Analyze the neuroprotective mechanisms of anthocyanins based on the described transcriptomic results.
• Study microglial polarization shifts based on the described in vitro and in vivo model findings.
• Investigate potential drug-target interactions based on the described molecular docking analysis between Dp3G and NLRC3.
• Validate findings on metabolic reprogramming and NF-κB signaling inhibition described in the results.

Strengths

• Includes results from both in vitro (oxygen–glucose deprivation model) and in vivo (neonatal KM mouse model) experiments.
• Employs multiple analysis techniques mentioned in the description, including transcriptomics and molecular docking.
• Published under a permissive CC-BY-4.0 license, allowing for reuse and redistribution.

Limitations

• The dataset is a 209 KB PDF; the underlying raw data files, column definitions, and row counts are unavailable.
• Description metadata is limited; actual data quality and structure require manual inspection after download.
• The study is based on a neonatal mouse model; direct applicability to human clinical contexts may be limited.

Provenance

Source

figshare, author Jiacan Xu

Collection Method

Experimental research using oxygen–glucose deprivation models, transcriptomic analysis, and molecular docking.

Time Range

Study published in 2026; specific experimental dates are not provided.

Freshness

Last updated 2026-05-04 05:30:31; freshness should be verified.

Geography

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