Data Sheet 1_Dendrobium officinale polysaccharide improves hair regrowth in androgenetic a
by Yuchen Ba·Updated 19d ago
1.7 MB1files
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Description
A dataset from figshare, authored by Yuchen Ba and last updated in May 2026, contains results from a study on androgenetic alopecia (AGA) in mice. It includes data from a dihydrotestosterone-induced mouse model evaluating the effects of Dendrobium officinale polysaccharide (DOP) on hair regrowth. The dataset likely contains histological assessments, quantitative proteomics, biochemical assays, and immunofluorescence results.
Use Cases
Analyze dose-response relationships for hair regrowth based on histological assessments of hair coverage and follicle density.
Investigate protein expression changes related to steroid hormone biosynthesis and estrogen signaling from the proteomic analysis.
Model the association between local steroid metabolite levels (dihydrotestosterone, testosterone) and follicular keratin expression (KRT28, KRT71).
Study spatial protein distribution shifts for targets like CYP19A1 and ESR1 within hair follicle structures using multiplex immunofluorescence data.
Strengths
Dataset is associated with a detailed experimental methodology including dose screening, proteomics, and pharmacological perturbation.
Results include quantitative measurements for multiple endpoints such as hair follicle density, dermal thickness, and protein expression levels.
Data is shared under a permissive CC-BY-4.0 license, facilitating reuse.
Limitations
Row count and specific column-level documentation are unknown, which may limit suitability assessment.
The dataset is small (1.7 MB), suggesting it may contain summary results rather than raw experimental data.
Description metadata is limited; actual data quality and structure require manual inspection after download.
Provenance
Source
figshare
Collection Method
Data generated from a dihydrotestosterone-induced mouse model of androgenetic alopecia, evaluated using histology, proteomics, biochemical assays, and immunofluorescence.
Freshness
Last updated 2026-05-18 05:43:02; freshness should be verified.
The primary data file is a ZIP archive; contents and specific file formats are not detailed in the provided metadata.