Data Sheet 1_Dendrobium officinale polysaccharide improves hair regrowth in androgenetic a

A dataset from figshare, authored by Yuchen Ba and last updated in May 2026, contains results from a study on androgenetic alopecia (AGA) in mice. It includes data from a dihydrotestosterone-induced mouse model evaluating the effects of Dendrobium officinale polysaccharide (DOP) on hair regrowth. The dataset likely contains histological assessments, quantitative proteomics, biochemical assays, and immunofluorescence results.

Use Cases

• Analyze dose-response relationships for hair regrowth based on histological assessments of hair coverage and follicle density.
• Investigate protein expression changes related to steroid hormone biosynthesis and estrogen signaling from the proteomic analysis.
• Model the association between local steroid metabolite levels (dihydrotestosterone, testosterone) and follicular keratin expression (KRT28, KRT71).
• Study spatial protein distribution shifts for targets like CYP19A1 and ESR1 within hair follicle structures using multiplex immunofluorescence data.

Strengths

• Dataset is associated with a detailed experimental methodology including dose screening, proteomics, and pharmacological perturbation.
• Results include quantitative measurements for multiple endpoints such as hair follicle density, dermal thickness, and protein expression levels.
• Data is shared under a permissive CC-BY-4.0 license, facilitating reuse.

Limitations

• Row count and specific column-level documentation are unknown, which may limit suitability assessment.
• The dataset is small (1.7 MB), suggesting it may contain summary results rather than raw experimental data.
• Description metadata is limited; actual data quality and structure require manual inspection after download.

Provenance

Source

figshare

Collection Method

Data generated from a dihydrotestosterone-induced mouse model of androgenetic alopecia, evaluated using histology, proteomics, biochemical assays, and immunofluorescence.

Freshness

Last updated 2026-05-18 05:43:02; freshness should be verified.