Emericellopsis XJ1056 Fungal Platform for Beauvericin Biosynthesis

Data Sheet 1 documents the development of the filamentous fungus Emericellopsis sp. XJ1056 as a platform for high-yield biosynthesis of the nonribosomal peptide beauvericin. The study, authored by Yutong Ai and shared on figshare in April 2026, details genetic engineering methods and fermentation optimization that achieved a yield of 921.24 mg/kg dry weight. This establishes a generalizable platform for heterologous production of diverse natural products.

Use Cases

• Benchmarking fungal platform performance based on reported yield metrics like 663.40 mg/kg and 921.24 mg/kg.
• Studying genetic toolkit effectiveness based on described methods such as Δku70 strain construction and homologous recombination efficiency improvements.
• Analyzing fermentation optimization strategies based on the use of solid media like rice supplemented with wheat bran.
• Investigating codon optimization impact based on the reported increase in transcriptional efficiency and beauvericin production.

Strengths

• Documentation includes specific quantitative results, such as a final beauvericin yield of 921.24 mg/kg dry weight.
• Describes a concrete methodological advance, increasing homologous recombination efficiency from 9.4% to 50–73.68%.
• Provides a direct comparison to prior benchmarks, surpassing a previously reported maximum yield of 98.56 mg/L.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for structured data analysis.
• The primary file format is DOCX, which may require conversion for computational analysis.

Provenance

Source

Yutong Ai via figshare.

Collection Method

Experimental research involving genetic engineering and fermentation optimization of a fungal strain.

Time Range

The study period is not specified.

Freshness

Last updated 2026-04-16 05:24:29; freshness should be verified.

Geography

Geographic coverage is not specified.