Core Outcome Set for Traditional Chinese Medicine in Atrial Fibrillation Trials

A consensus-driven core outcome set (COS) for clinical trials of traditional Chinese medicine (TCM) for atrial fibrillation (AF). The set was developed through a Delphi survey involving 87 participants and a consensus meeting with 19 stakeholders, resulting in seven recommended core outcomes. It aims to standardize outcome reporting and measurement in TCM-AF research.

Use Cases

• Standardizing outcome selection in TCM-AF clinical trials based on the seven recommended core outcomes.
• Comparing efficacy across different TCM interventions for AF based on metrics like episode frequency and duration.
• Assessing long-term prognosis and complication risks in AF patients using outcomes like thromboembolic event rate.
• Informing patient-centered care by incorporating TCM-specific symptom assessments like palpitation.
• Designing data collection protocols with recommended measurement instruments and time points.

Strengths

• Developed via a structured consensus process involving 87 Delphi survey participants and 19 stakeholders.
• Specifies seven concrete core outcomes, including AF episode metrics, symptoms, and complication risks.
• Provides recommendations for measurement instruments and time points for the outcomes.

Limitations

• The dataset is a 20.6 KB document describing the outcome set; the underlying clinical trial data is not included.
• Column-level documentation for any associated data is absent; field semantics must be inferred from the description.
• The scope is limited to the specific context of traditional Chinese medicine for atrial fibrillation.

Provenance

Source

figshare, authored by Chenyao Zhang.

Collection Method

Developed through literature review, registered trial analysis, physician surveys, patient interviews, and a two-round Delphi consensus process.

Freshness

Last updated 2026-05-07 05:42:53; freshness should be verified.