Oncopig High-Grade Glioma Model: Tumor Growth and Surgical Resection Data

A study from 2026 by Caleb Y. Kwon describes the development of a preclinical glioma surgery model using ten Oncopigs. Tumors were induced via viral vector and monitored with MRI, with six pigs developing tumors ranging from 250 to 2000 mm3 in volume. The dataset includes results from MRI tracking, surgical resection, and histopathological analysis of tumor specimens.

Use Cases

• Evaluating tumor growth kinetics based on MRI monitoring data mentioned in the description
• Assessing the pathological features of infiltrative brain tumors based on histopathological analysis results
• Testing fluorescence-guided surgical techniques based on the ALA-PpIX fluorescence finding
• Comparing preclinical model tumor volumes and onset times to human clinical data

Strengths

• Includes specific tumor volume measurements ranging from 250 to 2000 mm3
• Reports a median tumor onset time of 24 days across a cohort of ten animals
• Provides pathological confirmation that tumors were consistent with human high-grade glioma

Limitations

• Row count is unknown, which may limit suitability assessment
• Column-level documentation is absent; field semantics must be inferred after download
• The primary data file is a 1.5 MB DOCX document, which may not be a structured data format

Provenance

Source

Caleb Y. Kwon via figshare

Collection Method

Experimental study involving viral induction of tumors in a transgenic Oncopig model, followed by MRI monitoring, surgery, and tissue analysis.

Time Range

The study period is not specified, but the dataset was last updated in 2026.

Freshness

Last updated 2026-04-20 09:56:22; freshness should be verified