Infant Fecal Lactose and Gut Microbiome Data for Secondary Lactose Intolerance Research

A dataset from a study of secondary lactose intolerance in Chinese infants, investigating fecal lactose levels and gut microbial composition. The data includes results from in vitro fermentation assays and microbiota profiling, published by Jian Kuang on figshare. The dataset was last updated on April 21, 2026.

Use Cases

• Identifying microbial biomarkers for lactose intolerance based on described depletion of Bacteroidetes and certain Firmicutes.
• Correlating residual fecal lactose levels with clinical outcomes of secondary lactose intolerance.
• Modeling microbial fermentation dynamics using data from in vitro assays measuring acid, gas, and short-chain fatty acid production.
• Investigating the resilience of butyrate synthesis pathways under different nutrient conditions as described in the results.

Strengths

• Includes multi-modal data on fecal metabolites (lactose, lactate, SCFAs) and 16S rRNA microbiome profiling.
• Data is supported by in vitro fermentation assays across multiple media conditions (lactose, FOS, GOS, starch).
• Released under a permissive CC-BY-4.0 license, allowing for broad reuse and sharing.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for large-scale modeling.
• The geographic scope is implied to be China, which may limit generalizability to other populations.

Provenance

Source

figshare, author Jian Kuang.

Collection Method

Likely collected from clinical samples and subsequent laboratory assays as described in the study background and results.

Freshness

Last updated 2026-04-21 04:21:47; freshness should be verified.

Geography

The study background mentions infants in China, suggesting the data's primary geographic focus.