Yeast Vacuole Lipid Effects on Fusion, Fluidity, and Ion Transport

Experimental data examines the differential effects of lysophospholipids on yeast vacuole fusion, membrane fluidity, and ion transport. The dataset likely contains measurements of inhibition values, fluidity changes, and transport rates for various lipid headgroups and acyl chains. It was authored by Chi Zhang and uploaded to figshare on 2026-04-29.

Use Cases

• Modeling lipid inhibition effects on membrane fusion based on IC50 values.
• Analyzing relationships between lipid headgroup type and membrane fluidity.
• Investigating the impact of acyl chain length and saturation on calcium transport.
• Comparing the effects of lysophosphatidylcholine, lysophosphatidic acid, and lysophosphatidylethanolamine.

Strengths

• Specific IC50 values for lysophosphatidylcholine inhibition (40–120 µM) are provided.
• Experimental comparisons between different lipid headgroups (LPC, LPA, LPE) are detailed.
• The dataset focuses on multiple biophysical properties: fusion, fluidity, and ion transport.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is small (395.9 KB), indicating limited scope.

Provenance

Source

Chi Zhang

Collection Method

Likely contains experimental measurements from laboratory studies.

Freshness

Last updated 2026-04-29 05:57:13; freshness should be verified.