Functional Connectivity Data for IBS and Depression Study, 69 Participants

32 irritable bowel syndrome patients and 37 healthy controls underwent resting-state fMRI scans to explore brain connectivity. Xi Liu's 2026 study links prefrontal-sensorimotor functional connectivity to depression scores and IBS symptom severity. The 211.6 KB document details methods, results, and mediation analysis from this exploratory neuroimaging research.

Use Cases

• Validate brain connectivity biomarkers for IBS based on described functional connectivity strength (FCS) and seed-based analyses.
• Train models to predict symptom severity from neuroimaging features like PFC-SI connectivity mentioned in the results.
• Replicate mediation analysis exploring the role of aberrant rsFC between depression and IBS severity.
• Study default mode network (DMN) alterations in chronic pain conditions based on described connectivity with the angular gyrus.

Strengths

• Includes data from 69 participants (32 IBS patients, 37 healthy controls) as stated in the methods.
• Correlates specific neuroimaging metrics (e.g., left PFC FCS) with standardized clinical scores (SDS, IBS-SSS).
• Released under a permissive CC-BY-4.0 license for reuse and analysis.

Limitations

• Row count and column-level documentation are absent; field semantics must be inferred after download.
• The 211.6 KB size suggests the primary file is a methods/results document, not the raw underlying dataset.
• Data may reflect bias inherent to the specific exploratory study design and recruitment described.

Provenance

Source

figshare

Collection Method

Resting-state functional magnetic resonance imaging (rs-fMRI) scans analyzed with whole-brain FCS and seed-based FC methods.

Time Range

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Freshness

Last updated 2026-04-14 05:38:35; freshness should be verified.

Geography

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