Tobacco Craving Response Times in Neuromodulation Trial

Larissa Vieira's secondary analysis dataset from a randomized trial investigates response times to craving-item ratings in tobacco-dependent adults. The data originates from a cue-reactivity paradigm before and after a single 1 Hz rTMS session targeting either the left frontopolar cortex (n=12) or vertex (n=11). It examines the modulation of response time by stimulation site and its association with smoking outcomes at baseline and one-week follow-up.

Use Cases

• Analyze response time patterns as an implicit marker of cue-reactivity under different rTMS stimulation sites (lFPC vs. vertex).
• Model the relationship between self-reported craving ratings and associated response times to smoking and neutral cues.
• Examine exploratory clinical associations between response time indices and smoking-related outcomes like tonic craving.

Strengths

• Data is from a controlled randomized trial with two distinct stimulation groups (lFPC n=12, vertex n=11).
• Includes pre- and post-intervention measurements from a cue-reactivity paradigm for temporal comparison.
• Released under a permissive CC BY 4.0 license, allowing for broad reuse and analysis.

Limitations

• The dataset is very small, with only 23 total participants across two groups, limiting statistical power.
• Exploratory clinical analyses did not reveal reliable associations with smoking outcomes, indicating preliminary findings.
• Specific data structure, column names, and row counts are unknown, complicating immediate analysis.

Provenance

Source

Larissa Vieira via figshare.

Collection Method

Secondary analysis of a randomized trial where participants completed an image-based cue-reactivity paradigm before and after a single rTMS session.

Time Range

Measurements taken at baseline and one-week follow-up.

Freshness

Last updated on 2026-03-23.