Snakebite Envenomation Severity and Neutrophil-to-Lymphocyte Ratio

203 patient records from a retrospective cohort study analyze the association between admission neutrophil-to-lymphocyte ratio (NLR) and clinical severity in Gloydius brevicaudus envenomation. The study found a dose–response relationship, with the highest NLR quartile showing a nearly fourfold increased risk of moderate-to-severe envenomation. Data includes clinical severity scores, NLR values, and adjusted odds ratios from multivariable logistic regression.

Use Cases

• Analyze the dose–response relationship between admission NLR values and clinical severity scores to validate the reported adjusted odds ratios.
• Investigate the association of demographic and bite-related factors, used as covariates in the regression models, with envenomation severity outcomes.
• Examine the distribution of NLR across severity quartiles to replicate the trend test demonstrating increased risk in higher quartiles.
• Use the clinical severity score, dichotomized as mild or moderate-to-severe, as a target variable for predictive modeling with NLR as a key feature.

Strengths

• Contains data from 203 patients with confirmed Gloydius brevicaudus envenomation, providing a defined clinical cohort.
• Study methodology is detailed, including multivariable logistic regression and quartile-based trend testing for dose–response analysis.
• Findings are statistically grounded, reporting specific adjusted odds ratios (e.g., 3.94 for the highest NLR quartile) and confidence intervals.

Limitations

• The dataset is small at 19.1 KB, indicating limited scope and potentially insufficient for complex machine learning tasks.
• As a retrospective study, it may contain inherent biases from data collection methods and patient selection.
• Clinical and geographic context is unspecified, limiting generalizability to other snakebite envenomation scenarios.

Provenance

Source

figshare, authored by Yu-hong Wang.

Collection Method

Retrospective cohort study of hospital patients with confirmed envenomation.

Freshness

Last updated on 2026-03-25, indicating a forward-dated timestamp which may be a placeholder.