Data Sheet 1_Driving pressure-guided ventilation during one-lung ventilation for thoracic

Four randomized controlled trials involving 654 patients form the primary analysis of this systematic review. The study, authored by Xinrui Yin and published on figshare in May 2026, assesses the effects of driving pressure-guided ventilation on postoperative pulmonary complications in adults undergoing thoracic surgery. The overall certainty of evidence was graded as low due to inconsistency and imprecision.

Use Cases

• Assessing the efficacy of driving pressure-guided ventilation based on pooled risk ratios and confidence intervals from the meta-analysis.
• Evaluating methodological quality and evidence certainty in clinical trials based on the GRADE framework described.
• Identifying research gaps for future trials based on the hypothesis-generating conclusions and calls for larger, harmonized studies.

Strengths

• The review is registered in PROSPERO with a unique identifier (CRD420261329253), providing traceability.
• Includes a primary analysis of 4 RCTs and exploratory analyses of 6 trials, offering multiple analytical perspectives.
• Employs specific meta-analytic methods (restricted maximum likelihood estimation with Hartung–Knapp adjustment).

Limitations

• The dataset is a single 270.9 KB PDF document; the underlying trial data is not provided in a structured, machine-readable format.
• Row count and column-level documentation are unknown, limiting direct data analysis.
• The primary analysis result was not statistically significant, and the overall certainty of evidence is low.

Provenance

Source

Systematic review sourced from MEDLINE, Embase, CENTRAL, Web of Science, Scopus, and trial registries.

Collection Method

Literature search and meta-analysis of randomized controlled trials and observational studies.

Time Range

Literature searched from inception to 19 March 2026.

Freshness

Last updated 2026-05-20 05:23:34.

Geography

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