Drug-Coated Balloons vs. Drug-Eluting Stents: Meta-Analysis of 23 Randomized Trials

A systematic review and meta-analysis of randomized controlled trials comparing drug-coated balloons (DCB) and drug-eluting stents (DES) for coronary artery disease, published in 2026. The dataset includes pooled outcomes from 23 trials comprising 8,123 patients, with subgroup analyses by lesion type, vessel size, and clinical presentation. The data was compiled by author Yuting Wang.

Use Cases

• Compare efficacy and safety outcomes (e.g., TLR, DoCE) between DCB and DES based on the meta-analysis results.
• Analyze treatment effect heterogeneity based on lesion type (de novo vs. in-stent restenosis) mentioned in the description.
• Investigate the association between DCB coating type (paclitaxel vs. sirolimus) and cardiac death risk.
• Evaluate the impact of vessel size (small vessel disease) on target lesion revascularization.
• Model the interaction between treatment effect and clinical presentation (STEMI, NSTEMI, unstable angina).

Strengths

• Includes data from 23 randomized controlled trials, a substantial number for meta-analysis.
• Comprises 8,123 patient records, providing a meaningful sample size.
• Performs detailed subgroup analyses by lesion type, vessel size, clinical presentation, and DCB type.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Some findings, such as the cardiac death signal for paclitaxel-coated balloons, are exploratory and derived from post-hoc analyses with limited events.

Provenance

Source

figshare

Collection Method

Systematic review and meta-analysis of randomized controlled trials from PubMed, Embase, CENTRAL, and Web of Science.

Time Range

Trials from inception to March 2026.

Freshness

Last updated 2026-05-18 05:53:53; freshness should be verified.