Data Sheet 1_Dual role of Ninjurin-1 in myeloid cell adhesion and inflammation in relapse-

Coleen Thompson authored a research paper investigating the role of Ninjurin-1 in relapsing-remitting experimental autoimmune encephalomyelitis (RR-EAE), a model for multiple sclerosis. The 1.8 MB PDF, last updated on 2026-04-15, presents findings from flow cytometry, gene-expression profiling, and in vivo peptide blockade experiments. The study identifies Ninjurin-1 as a regulator of immune activation and central nervous system infiltration in this neuroinflammatory disease model.

Use Cases

• Analyzing the role of adhesion molecules in neuroinflammation based on the described investigation of Ninjurin-1.
• Studying myeloid cell activation and infiltration in autoimmune disease models based on the described flow cytometry and gene-expression data.
• Identifying candidate therapeutic targets for relapsing-remitting multiple sclerosis based on the described in vivo peptide blockade results.
• Correlating molecular marker expression with clinical disease severity based on the described findings in the RR-EAE model.

Strengths

• The dataset is a structured research paper with a clear, peer-reviewed-style description of methods and findings.
• The file is 1.8 MB, indicating a manageable download size for a document.
• It is licensed under CC-BY-4.0, permitting broad reuse with attribution.

Limitations

• The primary data (e.g., raw flow cytometry, gene expression values) is not directly accessible; only the summarized findings in PDF format are provided.
• Row count and column-level documentation are absent, limiting suitability assessment for direct computational analysis.
• The data is specific to an animal model (RR-EAE), which may not directly translate to human multiple sclerosis.

Provenance

Source

Coleen Thompson via figshare.

Collection Method

Findings from experimental methods including flow cytometry, gene-expression profiling, and in vivo peptide blockade.

Time Range

The study period is not specified.

Freshness

Last updated 2026-04-15 04:37:06.

Geography

The geographic origin of the research is not specified.