Systematic Review on Brain-Muscle Interaction Dynamics During Neuromuscular Fatigue

Sarah Al Omari's systematic review, published on figshare in April 2026, synthesizes evidence on how neuromuscular fatigue affects brain-muscle communication. The review includes 15 non-randomized experimental studies involving 188 participants, predominantly neurologically healthy adults. It analyzes changes in corticomuscular coherence (CMC) derived from EEG and EMG recordings during various fatiguing tasks.

Use Cases

• Informing the design of future rehabilitation trials based on synthesized evidence of fatigue-related CMC changes.
• Analyzing task-dependent adaptations in brain-muscle communication based on the review's findings on contraction type and intensity.
• Comparing CMC modulation patterns between healthy and neurological populations based on the sparse evidence highlighted.
• Studying frequency-band specific coherence (e.g., beta band) changes during fatigue progression as reported across the included studies.

Strengths

• Systematic methodology with independent screening and data extraction by two reviewers.
• Includes data from 15 studies involving 188 total participants.
• Clear synthesis of heterogeneous CMC responses linked to specific task demands and fatigue stages.

Limitations

• The dataset is a 53.4 KB DOCX document, indicating a limited textual summary rather than raw experimental data.
• Row count and column-level documentation for any underlying data are absent; field semantics must be inferred from the review text.
• Evidence from neurological populations is sparse, based on only 14 individuals.

Provenance

Source

figshare, authored by Sarah Al Omari.

Collection Method

Systematic review of PubMed, Web of Science, and Embase up to February 2026.

Time Range

Literature search conducted up to 02/02/2026.

Freshness

Last updated 2026-04-20 04:11:49.

Geography

Studies included are not geographically specified; likely international.