Mouse Mandibular Molar Single-Cell RNA-Seq Data from E12.5 to E14.5

E12.5–E14.5 single-cell RNA-seq data from a reanalysis of public datasets, characterizing epithelial state changes during early mouse molar development. The dataset was created by Yuanjing Jiang and is licensed under CC-BY-4.0. It was last updated on 2026-05-19.

Use Cases

• Analyze temporal gene expression shifts based on the described transition from proliferative odontogenic activity to ECM-adhesion remodeling.
• Investigate cell-matrix interaction pathways based on the mention of ECM components and focal adhesion-related pathways.
• Validate spatial patterns of epithelial invagination based on the integration of transcriptomic and morphometric findings described.
• Study signaling pathways like Wnt and Hippo based on their reported enrichment in early-stage epithelial cells.

Strengths

• Dataset is small at 1.3 MB, facilitating quick download and local analysis.
• Provides a stage-matched reanalysis across three specific embryonic days (E12.5, E13.5, E14.5).

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.

Provenance

Source

figshare

Collection Method

Reanalysis of publicly available single-cell RNA-seq datasets, combined with morphometric and spatial validation.

Time Range

E12.5 to E14.5 (mouse embryonic days)

Freshness

Last updated 2026-05-19 04:20:56; freshness should be verified.