Systematic Review of Transversus Abdominis Plane Block for Post-Nephrectomy Pain

A 2026 systematic review and meta-analysis by Wei Huang, aggregating data from 10 randomized controlled trials involving 639 patients. The document evaluates the effect of transversus abdominis plane block on postoperative pain, opioid consumption, and adverse reactions following nephrectomy. It was published on figshare under a CC-BY-4.0 license.

Use Cases

• Evaluating the efficacy of a specific nerve block for postoperative pain management based on aggregated trial results.
• Analyzing trends in opioid consumption reduction based on meta-analysis findings of intravenous morphine equivalents.
• Comparing resting and active pain score trajectories at multiple postoperative time points based on the reported statistical outcomes.
• Assessing the impact of an analgesic intervention on postoperative hospital stay and gastrointestinal adverse reactions based on the review's conclusions.

Strengths

• The analysis is based on 10 randomized controlled trials, a standard for clinical evidence.
• Includes data from 639 total patients, providing a quantifiable sample size for the meta-analysis.
• Reports specific statistical outcomes, including mean differences, confidence intervals, and p-values for multiple endpoints.
• Follows a documented methodology including search across seven databases and use of GRADEpro for evidence grading.

Limitations

• The dataset is a single 540.5 KB DOCX document; the underlying trial data is not provided in a structured, machine-readable format.
• Row count and column-level documentation for any underlying data are unknown.
• The description metadata is limited to the review's abstract; data quality and granularity require manual inspection after download.

Provenance

Source

Wei Huang, published on figshare.

Collection Method

Systematic review and meta-analysis of randomized controlled trials identified via database search.

Time Range

Database inception to 31 January 2026.

Freshness

Last updated 2026-06-03.