Meta-Analysis of Skull Base-Peripheral Acupuncture for Post-Stroke Cognitive Impairment

A systematic review and meta-analysis of 24 randomized controlled trials involving 1,962 patients, published on figshare in 2026. The study evaluates the efficacy and safety of skull base-peripheral acupuncture for post-stroke cognitive impairment. The author is Yinyi Xiong, and the work is licensed under CC-BY-4.0.

Use Cases

• Assess the clinical effective rate of skull base-peripheral acupuncture based on the reported odds ratio (OR=3.84).
• Analyze changes in cognitive function scores based on reported Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA) outcomes.
• Evaluate improvements in activities of daily living (ADL) based on the reported standardized mean difference (SMD=1.62).
• Investigate subgroup effects based on reported findings for combination therapy and treatment duration under three months.

Strengths

• Includes data from 24 randomized controlled trials, providing a multi-study synthesis.
• Reports specific meta-analysis results including odds ratios, mean differences, and confidence intervals for four primary outcomes.
• Explicitly registered with PROSPERO (CRD420251142773), indicating a structured review protocol.
• No serious adverse events were reported across the included studies, suggesting a likely favorable safety profile.

Limitations

• The dataset is a 283.0 KB DOCX document; the underlying trial-level data is not provided in a structured, machine-readable format.
• The description notes substantial heterogeneity in the meta-analysis and methodological limitations in the included trials.
• The author's organization is unknown, and column-level documentation for any potential supplementary data is absent.

Provenance

Source

figshare

Collection Method

Systematic review and meta-analysis of randomized controlled trials from eight Chinese and English databases.

Time Range

Literature searched from database inception to July 2025.

Freshness

Last updated 2026-04-30 04:21:12.