Data Sheet 1_Effects of aerobic exercise on vascular endothelial function and markers of o

A 12-week randomized controlled trial protocol investigates the effects of supervised aerobic exercise on vascular endothelial function in 70 individuals with impaired glucose tolerance. The study, authored by Hancheng Wu, includes primary and secondary endpoints measuring flow-mediated dilation, cardiovascular function, and inflammatory biomarkers. Recruitment for this assessor-blinded trial commenced in August 2025.

Use Cases

• Analyzing the relationship between aerobic exercise and endothelial function based on flow-mediated dilation measurements.
• Studying the regulatory roles of oxidative stress and inflammation based on circulating biomarker data.
• Modeling the effects of exercise on glucose and lipid metabolism based on secondary endpoint variables.
• Investigating ex vivo endothelial cell function based on serum transfer experiments with HUVECs and EPCs.

Strengths

• The protocol describes a randomized controlled trial with an assessor-blinded design, which suggests methodological rigor.
• The study includes 70 participants and measures multiple endpoints, including primary (FMD) and secondary (biomarkers, metabolism) outcomes.
• The document is licensed under CC-BY-4.0, allowing for reuse and sharing.

Limitations

• The dataset is a 671.1 KB DOCX file containing a study protocol, not the underlying clinical trial data itself.
• Column-level documentation and sample data are unavailable, making direct analysis of the trial results impossible from this file.
• The row count and specific data structure are unknown, limiting suitability assessment for computational tasks.

Provenance

Source

figshare, author Hancheng Wu

Collection Method

Study protocol document for a randomized controlled trial.

Time Range

Recruitment commenced August 2025; trial duration is 12 weeks.

Freshness

Last updated 2026-04-30 04:18:37; freshness should be verified.