Scoping Review on Dexmedetomidine Effects for Perioperative Neurocognitive Disorders

Twenty-seven studies involving 9,890 elderly patients synthesize evidence on dexmedetomidine's effects on perioperative neurocognitive disorders. Jinxiang Xie authored this scoping review, which was last updated on May 11, 2026. The analysis reveals inconsistent outcomes across different disorder subtypes and assessment timings.

Use Cases

• Systematic evidence synthesis based on the review's thematic analysis of 27 studies
• Comparative analysis of drug effects based on reported outcomes across PND subtypes like dNCR and POD
• Methodological review based on the noted heterogeneity in DEX protocols and diagnostic criteria

Strengths

• Synthesizes data from 27 studies encompassing 9,890 patients
• Follows PRISMA-ScR guidelines for systematic scoping review methodology
• Explicitly analyzes outcomes by PND subtype and assessment timing

Limitations

• Dataset is a single 834.6 KB DOCX document, limiting computational analysis
• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment

Provenance

Source

figshare

Collection Method

Systematic literature review following PRISMA-ScR guidelines, searching PubMed, Embase, and Cochrane Library.

Freshness

Last updated 2026-05-11 05:29:48