Systematic Review of Exercise Effects on Mitochondrial Myopathy, 157 Patients

Qiliang Wan's systematic review analyzes 15 clinical trials involving 157 patients with mitochondrial myopathy. The review, published on figshare in April 2026, investigates the effects of aerobic and resistance exercise on muscle function and mitochondrial markers. It covers studies from 1990 to September 2025.

Use Cases

• Analyzing the efficacy of moderate-intensity aerobic exercise based on reported improvements in VO2 max and PCr recovery.
• Evaluating the impact of resistance training based on reported increases in muscle strength and satellite cell activation.
• Comparing phenotype-specific responses to exercise based on reported outcomes for patients with m.3243A>G mutations versus other mutations.
• Assessing the methodological quality of clinical trials based on the use of RoB 2 and ROBINS-I V2 tools mentioned in the description.

Strengths

• Includes 157 patient records from 15 clinical trials.
• Provides a detailed methodological assessment using Cochrane and ROBINS-I tools.
• Covers a temporal range of studies from 1990 to September 2025.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is a 669.7 KB DOCX file, which is a small, text-only summary of findings.

Provenance

Source

figshare

Collection Method

Systematic review of literature from PubMed, Web of Science, Embase, and Scopus.

Time Range

1990 to September 2025

Freshness

Last updated 2026-04-09 05:15:32; freshness should be verified.