Data Sheet 1_Efficacy and safety of acupuncture-related therapies in improving insulin res

A systematic review and network meta-analysis of 53 randomized controlled trials involving 4,406 participants, published up to September 2025. The study compares 12 acupuncture-related therapy regimens for improving insulin resistance, reproductive endocrine outcomes, and ovarian morphology in women with polycystic ovary syndrome. The analysis was conducted by Zhenping Du and published on figshare in March 2026.

Use Cases

• Ranking the efficacy of different acupuncture therapies based on SUCRA values for outcomes like HOMA-IR and testosterone.
• Comparing mean differences in clinical outcomes such as BMI, WHR, and antral follicle count across interventions.
• Assessing the safety profile of acupuncture-related therapies based on reported adverse event data.
• Training models to predict treatment effectiveness for PCOS based on network meta-analysis results.

Strengths

• Analysis is based on 53 randomized controlled trials, providing a substantial evidence base.
• Includes data from 4,406 participants, offering a meaningful sample size for meta-analysis.
• Explicitly registered with PROSPERO (CRD420251151249), indicating a structured review protocol.
• Reports specific mean differences and confidence intervals for over 10 clinical outcomes.

Limitations

• The primary data file is a 3.0 MB DOCX document; the underlying trial data is not provided in a structured, machine-readable format.
• Adverse-event reporting was noted as limited across the included trials, which may affect safety conclusions.
• Row count and column-level documentation for any underlying data are unknown.

Provenance

Source

Systematic review compiled by author Zhenping Du from eight databases including Cochrane Library, PubMed, and CNKI.

Collection Method

Network meta-analysis of randomized controlled trials retrieved from literature databases.

Time Range

Literature search conducted up to September 2025.

Freshness

Last updated 2026-03-18 07:44:52.

Geography

Trials in Chinese and English were included; specific geographic coverage of primary studies is not stated.