Systematic Review of Buyang Huanwu Decoction and α-Lipoic Acid for Diabetic Neuropathy

Qi Yong's systematic review and meta-analysis evaluates the efficacy and safety of Buyang Huanwu Decoction combined with α-lipoic acid for diabetic peripheral neuropathy. The analysis includes 12 randomized controlled trials involving 926 patients, sourced from databases including PubMed, Web of Science, and CNKI up to December 2025. It provides a methodological framework for heterogeneity deconstruction and was last updated on 2026-04-30.

Use Cases

• Assessing treatment efficacy based on overall response rate and TCM syndrome score metrics
• Analyzing heterogeneity in nerve conduction velocity outcomes using the described multi-tiered framework
• Evaluating safety profiles based on adverse event data mentioned in the review
• Studying trends in oxidative stress markers like SOD, MDA, and T-AOC

Strengths

• Includes data from 12 randomized controlled trials with a total of 926 patients
• Employs a detailed five-tiered framework for heterogeneity analysis as described
• Reports specific effect sizes, such as RR=1.24 for overall response rate and SMD=-0.76 for TCM syndrome scores

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• The primary data file is a 196.8 MB DOCX document, which may require parsing to extract structured data
• Row count is unknown, which may limit suitability assessment

Provenance

Source

figshare, author Qi Yong

Collection Method

Systematic review and meta-analysis of randomized controlled trials from multiple databases.

Time Range

Literature search conducted up to December 2025.

Freshness

Last updated 2026-04-30 04:18:16