Enterococcus faecium HDRsEf1 Effects on Gut Microbiota and Metabolites in Mice and Pigs

A research paper details the impact of the probiotic Enterococcus faecium HDRsEf1 on host health. The study uses DSS-induced colitis in mice and nursery pig models to evaluate changes in gut microbiota composition and fecal metabolite profiles. The 189.8 KB PDF was authored by Shuaifei Feng and last updated in April 2026.

Use Cases

• Analyze probiotic effects on inflammatory markers based on measured IL-1β, IL-6, TNF-α, and IL-10 levels
• Study gut microbiota modulation based on reported changes in genera like Ruminococcus, Acetobacter, and Acinetobacter
• Investigate links between metabolites and host health based on described anti-inflammatory metabolite enrichment
• Compare host responses across species based on data from both mouse and pig models

Strengths

• Data is derived from controlled animal models (mice and pigs) for biological validation.
• Specific inflammatory and oxidative stress markers (IL-1β, MDA, SOD) are measured and reported.
• The dataset is openly available under a CC-BY-4.0 license.

Limitations

• The primary data file is a 189.8 KB PDF; underlying raw data tables are not directly accessible.
• Row count and column-level documentation for any underlying data are unknown.
• The dataset's small size (189.8 KB) indicates limited scope, likely containing summary results rather than extensive raw data.

Provenance

Source

figshare, author Shuaifei Feng

Collection Method

Experimental study using DSS-induced colitis in mice and nursery pig models.

Time Range

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Freshness

Last updated 2026-04-15 04:37:11

Geography

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