Estimated Pneumococcal Disease Burden in Children Across Five Latin American Countries

A static Excel-based model estimates annual pneumococcal disease cases, deaths, and costs attributable to vaccine serotypes in children under five. The analysis covers Argentina, Chile, Mexico, Colombia, and Brazil, using country-specific epidemiological, cost, and population inputs. Sophie Warren authored this study, which was last updated on 2026-05-21.

Use Cases

• Compare the clinical burden of serotypes covered by PCV10, PCV13, PCV15, and PCV20 vaccines based on the described model outputs.
• Analyze the economic and societal cost distribution between invasive and non-invasive pneumococcal disease types mentioned in the results.
• Evaluate the potential public health impact of switching from PCV10 or PCV13 to PCV20 based on the estimated burden of serotypes unique to PCV20.
• Assess country-specific disease burden patterns across the five Latin American nations described.

Strengths

• Focuses on five specific countries: Argentina, Chile, Mexico, Colombia, and Brazil.
• Estimates over 510,000 annual cases and approximately 2,700 deaths attributable to PCV20 serotypes.
• Quantifies economic burden exceeding USD $182 million and societal burden exceeding USD $34 million annually.
• Distinguishes burden by vaccine serotype groups (PCV10, PCV13, PCV15, PCV20) and by disease type (invasive vs. non-invasive).

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is a single PDF file of 219.9 KB, likely containing summary tables rather than raw, granular data.

Provenance

Source

figshare

Collection Method

A static Excel-based model applied country-specific epidemiological, cost, and population inputs.

Freshness

Last updated 2026-05-21 05:42:29; freshness should be verified.

Geography

Argentina, Chile, Mexico, Colombia, Brazil