Fecal Microbiota Transplantation Effects on HIV-Infected Humanized Mice

1.1 MB of multi-omics data from a study comparing HIV-infected dHu-BLT mice treated with ART alone versus ART plus FMT. The dataset includes results from 16S rRNA sequencing, RNA-seq, and immune assays, authored by Saroj Chandra Lohani and last updated in June 2026. It was released under a CC-BY-4.0 license on figshare.

Use Cases

• Analyze changes in gut microbial composition based on 16S rRNA sequencing data mentioned in the description.
• Profile transcriptomic changes in intestinal tissue based on RNA-seq data mentioned in the description.
• Correlate microbial shifts with inflammatory marker levels based on plasma markers like CD62E and sCD14 mentioned in the description.
• Investigate pathway activation, such as extracellular matrix organization, based on predicted pathway analysis mentioned in the description.

Strengths

• Dataset is 1.1 MB in size, indicating a focused and likely manageable collection.
• The description details a multi-omics approach combining 16S rRNA sequencing and RNA-seq.
• Specific inflammatory markers measured, including CD62E, sCD14, sCD163, and FABP2, are named.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The primary data file is a DOCX format, which may require extraction of underlying data tables.

Provenance

Source

figshare

Collection Method

Experimental data from a study using a double humanized-BLT (dHu-BLT) mouse model, analyzed via multi-omics and immune assays.

Freshness

Last updated 2026-06-03 04:47:37; freshness should be verified.