E. coli Growth and Transcriptomic Responses to Wastewater Effluent and Tetracycline Stress

A study by Alejandra R. Chavez, last updated March 2026, examines how filtered wastewater effluent affects Escherichia coli. The data includes growth assay results and RNA sequencing transcriptomics from experiments with simultaneous exposure to effluent and tetracycline antibiotic. The findings indicate the effluent promotes antibiotic tolerance by altering growth dynamics without changing genetic resistance.

Use Cases

• Modeling bacterial growth dynamics under combined chemical stress based on lag phase duration data.
• Analyzing transcriptomic adaptation to environmental stressors based on differential gene expression profiles.
• Investigating the link between wastewater chemistry and antibiotic tolerance development.
• Assessing ecosystem risks from wastewater effluent discharge containing antibiotics.

Strengths

• Data is associated with a detailed scientific study published on figshare.
• Includes both physiological (growth assays) and transcriptomic (RNA-seq) response data.
• License is CC-BY-4.0, permitting open sharing and adaptation.

Limitations

• Row count and column-level documentation are unknown, limiting suitability assessment.
• The dataset is small at 589.8 KB, indicating limited scope.
• The primary file format is PDF, which may require extraction for computational analysis.

Provenance

Source

Alejandra R. Chavez via figshare

Collection Method

Laboratory growth assays and RNA sequencing performed on E. coli cultures.

Time Range

Experimental timeframe is not specified.

Freshness

Last updated 2026-03-23 06:30:29

Geography

Geographic origin of the wastewater effluent is not specified.