Insula Functional Connectivity Gradients in Major Depressive Disorder, 72 Subjects

A 403.3 KB PDF dataset from figshare, last updated April 2026, containing results from a study by Birce Begum Burhanoglu. It compares functional connectivity gradients of the insula between 38 patients with major depressive disorder and 34 healthy controls using resting-state fMRI data.

Use Cases

• Analyzing differences in whole-brain functional gradient organization between MDD patients and healthy controls.
• Investigating altered anterior-posterior insula gradient separation in major depressive disorder.
• Studying the specialized functional relationship between the insula and the dorsal attention network in MDD.

Strengths

• Data is derived from a controlled study with 72 total subjects (38 MDD patients, 34 healthy controls).
• Analysis performed at three levels: whole-brain, insula-to-whole-brain, and insula-to-seven-brain-networks.
• Dataset is openly licensed under CC-BY-4.0.

Limitations

• Row count and column-level documentation are absent; field semantics must be inferred after download.
• The dataset is small (403.3 KB), suggesting it contains summary results rather than raw data.
• The data format is PDF, which may require extraction for computational analysis.

Provenance

Source

figshare, author Birce Begum Burhanoglu.

Collection Method

Resting-state functional MRI data collection and gradient analysis.

Time Range

Study period not specified in metadata.

Freshness

Last updated 2026-04-15 05:43:59.

Geography

Geographic coverage of subject recruitment not specified.