Galectin-3-FBXL5-YAP1 Axis in Colorectal Cancer: Gene Expression and Survival Data

Xiang Zeng's research data from 2026 investigates the Galectin-3-FBXL5-YAP1 signaling axis in colorectal cancer. The dataset likely contains gene expression correlations and survival analysis results from TCGA and single-cell RNA sequencing data. It was published on figshare under a CC-BY-4.0 license.

Use Cases

• Correlating LGALS3 and FBXL5 gene expression with patient survival outcomes based on the described clinical significance analysis.
• Investigating protein-protein interaction networks involving Galectin-3, FBXL5, and YAP1 based on the described co-immunoprecipitation assays.
• Modeling the impact of the Gal-3-FBXL5-YAP1 axis on tumor growth using data from the described xenograft mouse models.
• Analyzing post-transcriptional regulatory mechanisms through ubiquitination pathways based on the described protein degradation findings.

Strengths

• Data is associated with a specific mechanistic study published on figshare, providing biological context.
• The dataset is licensed under CC-BY-4.0, permitting open sharing and adaptation.
• The description details integration of TCGA and single-cell RNA sequencing data sources.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is small at 156.7 KB, indicating limited scope.

Provenance

Source

figshare

Collection Method

Likely contains integrated analysis results from TCGA and single-cell RNA sequencing data, plus experimental results from molecular and functional assays.

Freshness

Last updated 2026-04-21 05:24:26; freshness should be verified.