Limosilactobacillus reuteri HDB Genome from an Indian Infant Gut

Indian infant gut isolate Limosilactobacillus reuteri strain HDB genome, comprising a single circular 2,226,956 bp chromosome. The dataset includes functional annotation for vitamin B12 biosynthesis and probiotic genes, plus comparative analysis with 59 other L. reuteri genomes. Author Hemang D. Brahmbhatt uploaded the data to figshare in April 2026.

Use Cases

• Comparative genomics analysis based on the pangenome of 11,725 gene families.
• Probiotic candidate evaluation based on annotated genes for reuterin production and vitamin B12 biosynthesis.
• Phylogenetic placement of bacterial strains based on core-genome phylogeny aligning HDB with reference strain DSM 17938.
• Metabolic modeling based on predicted expanded carbohydrate flux in the HDB strain.

Strengths

• Complete genome assembly of a single circular chromosome (2,226,956 bp) with GC content of 39.04%.
• Functional annotation identifies genes for specific probiotic functions like vitamin B12 biosynthesis.
• Comparative analysis includes 59 other L. reuteri genomes, defining a pangenome of 11,725 gene families.

Limitations

• Data is provided as a DOCX document (1.3 MB), not a structured genomic data file.
• Row count and column-level documentation for any underlying data are unknown.
• Conclusions are based on computational predictions and require experimental validation as noted in the description.

Provenance

Source

figshare, author Hemang D. Brahmbhatt.

Collection Method

Hybrid de novo assembly using Illumina and Oxford Nanopore GridION MK1 sequencing.

Freshness

Last updated 2026-04-17 05:08:33.

Geography

Isolated from the gut of a healthy Indian infant.